Scientists have already learned how to use CRISPR to edit errors in almost any genome — and it’s these errors that can cause a wide range of diseases. Many forms of cancer, Huntington’s disease, and even HIV can be targeted using CRISPR. That being said, it’s not a perfect solution. Just as the autocorrect on your smartphone can cause you to send an unintentional and embarrassing text message, CRISPR can “correct” something that was actually right — the consequences of which can make it a dangerous mistake. One that actually causes a disease as opposed to an embarrassing social gaffe.The researchers developed a method for quickly testing a CRISPR molecule against a person’s entire genome, rather than only the target area, in order to predict other segments of DNA the tool might accidentally interact with. This new technique functions like an early warning system, giving doctors a chance to more closely tailor gene therapies to specific patients, while ensuring they are effective and safe.
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